When Not to Use:

• Allergic to Zyloric or its components
• Severe liver or kidney impairment
• Pregnant or breastfeeding

Warnings:

1. Regular monitoring of liver function advised
2. Adequate fluid intake to prevent kidney stones
3. Avoid alcohol consumption
4. Inform healthcare provider of ongoing medications
5. Exercise caution in elderly patients

Dosage:

• Initial: 100 mg daily, may be adjusted based on response
• Maintenance: 200-600 mg/day in divided doses

Interactions with Other Medicines, Alcohol, etc.:

1. Drug Interactions:

   • Warfarin: Increased risk of bleeding
   • Azathioprine: Enhanced toxicity
   • Theophylline: Increased theophylline levels

2. Alcohol Interaction:

   • Limited alcohol intake is advised to prevent exacerbating liver function abnormalities.

3. Food Interactions:

   • Avoid excessive intake of purine-rich foods.

4. Other Medications:

   • Diuretics: Increased risk of skin reactions
   • ACE inhibitors: Enhanced risk of allergic reactions

5. Herbal Interactions:

   • Avoid concurrent use with St. John’s Wort.

General Instructions:

1. Take with or after meals to minimize gastrointestinal discomfort.
2. Complete the prescribed course even if symptoms subside.
3. Report any unusual reactions promptly to a healthcare professional.
4. Routine blood tests may be required for monitoring.

How It Works:

Zyloric 100 mg Tablet exerts its therapeutic influence by inhibiting xanthine oxidase, a key enzyme involved in the production of uric acid. By curbing uric acid synthesis, it prevents the crystallization that leads to the formation of painful gouty deposits and kidney stones.